A key requirement for safety-critical systems that use Commercial Off-The- Shelf (COTS) components is that the COTS components do not compromise the reliability, safety and security of the overall system. Safety wrappers can be seen as a means to control the integration of the (often disparate in nature) components to ensure fault tolerance, quality of service and security. This paper discusses new strategies to enhance safety wrappers using a nuclear protection system example. It also illustrates a Perturbation of Interface Parameters (PIP) technique to aid and assess the new designs.